Role of nitric oxide in prevention diabetic nephropathy in females after menopause

Background: Type 2 diabetes mellitus (T2DM) is a complex disease, which affects many organs besides the pancreas such as liver, brain, eye, stomach, and kidney. Purpose: The current study aimed to evaluate role of nitric oxide in prevention diabetic nephropathy females after menopause. Methods: Our was carried out on 90 males with T2DM aged over 45 years, randomly selected from outpatient clinic National Institute for Diabetes Endocrinology (NIDE). patients were divided into 3 subgroups; subgroup 1: without any complications, 2: complications (DN), 3: cardiovascular compactions (CVD). Results: Result showed that dyslipidemia oxidative stress more pronounced rather than male. While, kidney function markers worse male female. Conclusion: shows are susceptible disease due depletion estrogen postmenopausal women, causing stress. On other hand, decrease level, considered protective factor.